Description

n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanamide is a specialized organoboron compound featuring a propanamide-linked phenylboronic ester. This matters because it serves as a versatile and stable synthetic intermediate, crucial for advanced organic synthesis and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling reactions and as a building block for bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring boronic acid/ester functionality.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a stable, air-handleable boronic ester partner for palladium-catalyzed carbon-carbon bond formation to create biaryl structures.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides that incorporate boron-containing motifs.
• Material Science Research: Serves as a precursor for boron-doped organic electronic materials, polymers, and sensors.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes.
• Organic Synthesis Building Block: Provides a protected boronic acid group for multi-step synthetic sequences where stability is required.

Basic Information

Product Name	n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanamide
CAS No.	1315571-00-6
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-propylbenzamide; N-Propyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylpropanamide; Propanamide, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; Benzamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-propyl-; B-3-(Propylcarbamoyl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.