Description

2-Pyridinecarboxaldehyde, 5-Cyclopropyl-3-Fluoro- is a specialized pyridine derivative that serves as a high-value building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a cyclopropyl group and a fluorine atom on the pyridine ring, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry for creating new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropyl and fluorine substituents contribute to enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways in academic and industrial research.

Basic Information

Product Name	2-Pyridinecarboxaldehyde, 5-Cyclopropyl-3-Fluoro-
CAS No.	1315363-79-1
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	5-Cyclopropyl-3-fluoropyridine-2-carbaldehyde; 3-Fluoro-5-cyclopropylpyridine-2-carboxaldehyde; 5-Cyclopropyl-3-fluoro-2-pyridinecarboxaldehyde; 2-Formyl-5-cyclopropyl-3-fluoropyridine; 5-Cyclopropyl-3-fluoropicolinaldehyde
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxaldehyde, 5-Cyclopropyl-3-Fluoro- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC, GC, and NMR characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.