Description

6-(Cyclobutylamino)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Cross-Coupling Reactions: Specifically designed as a boronic ester reagent for efficient and selective Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures.
• Chemical Biology: Employed in the synthesis of molecular probes and ligands for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	6-(Cyclobutylamino)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1315350-34-5
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	6-(Cyclobutylamino)-2-pyridineboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(cyclobutylamino)pyridine; 6-Cyclobutylaminopyridine-2-boronic acid pinacol ester; 6-(N-Cyclobutylamino)pyridine-2-boronic acid pinacol ester; 6-Cyclobutylaminopyridin-2-ylboronic acid pinacol ester; B-[6-(Cyclobutylamino)-2-pyridinyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 6-(Cyclobutylamino)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.