Description

2-Chloro-1-Methylimidazole-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Enables the synthesis of functional polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology: Serves as a probe or linker in bioconjugation and the development of biochemical tools.
• Cross-Coupling Reactions: Specifically designed as a versatile electrophilic partner in palladium-catalyzed Suzuki-Miyaura couplings.
• Heterocyclic Chemistry: Facilitates the efficient introduction of functionalized imidazole rings into complex molecular architectures.

Basic Information

Product Name	2-Chloro-1-Methylimidazole-5-Boronic Acid Pinacol Ester
CAS No.	1315281-29-8
Molecular Formula	C₁₀H₁₆BClN₂O₂
Molecular Weight	242.51 g/mol
Synonyms	2-Chloro-1-methyl-1H-imidazole-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chloro-1-methyl-1H-imidazole; 1-Methyl-2-chloroimidazole-5-boronic acid pinacol ester; 2-Chloro-1-methylimidazol-5-ylboronic acid pinacol ester; (2-Chloro-1-methyl-1H-imidazol-5-yl)boronic acid pinacol ester; 1315281-29-8; B-(2-Chloro-1-methyl-1H-imidazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Methylimidazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.