Description

5,5,5-Trifluoropent-2-enoic Acid is a high-value fluorinated building block characterized by its reactive α,β-unsaturated carboxylic acid moiety and terminal trifluoromethyl group. This unique structure makes it a critical intermediate for introducing fluorine atoms into target molecules, enhancing their metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology, CNS, and metabolic disease research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials, improving performance and stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing chemical resistance, surface properties, and durability.
• Organic Synthesis & Catalysis: A versatile reagent for Michael addition reactions and other transformations in complex molecule construction.
• Fluorinated Surfactant Precursor: Used in the manufacture of specialty surfactants with superior wetting and leveling properties.

Basic Information

Product Name	5,5,5-Trifluoropent-2-enoic Acid
CAS No.	1314994-88-1
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	5,5,5-Trifluoropent-2-enoic acid; (E)-5,5,5-Trifluoropent-2-enoic acid; 5,5,5-Trifluoro-2-pentenoic acid; 3-(Trifluoromethyl)but-2-enoic acid; 2-Pentenoic acid, 5,5,5-trifluoro-; TFP Acid; 1314994-88-1
EINECS	Contact for details

Quality Control

Every batch of 5,5,5-Trifluoropent-2-enoic Acid is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as bases, oxidizing agents, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.