Description

1-Bromo-4-(Dimethoxymethyl)-2-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring both a bromine substituent and a protected aldehyde group (dimethoxymethyl), makes it an essential intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring trifluoromethyl and bromoaryl motifs for bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where the benzene core provides a stable platform for functionalization.
• Material Science: Serves as a building block for organic electronic materials, including ligands for catalysts and monomers for specialty polymers.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig aminations.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-Bromo-4-(Dimethoxymethyl)-2-(Trifluoromethyl)Benzene
CAS No.	1314987-38-6
Molecular Formula	C10H10BrF3O2
Molecular Weight	299.09 g/mol
Synonyms	4-Bromo-α,α-dimethoxy-3-(trifluoromethyl)benzyl alcohol (dimethyl acetal); 2-(Trifluoromethyl)-4-bromobenzaldehyde dimethyl acetal; 1-Bromo-4-(dimethoxymethyl)-2-(trifluoromethyl)benzene; Benzene, 1-bromo-4-(dimethoxymethyl)-2-(trifluoromethyl)-; 4-Bromo-3-(trifluoromethyl)benzaldehyde dimethyl acetal
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-4-(Dimethoxymethyl)-2-(Trifluoromethyl)Benzene is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.