Description

4-Fluoro-Cyclohexylamine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the cyclohexyl scaffold's conformational properties and the fluorine atom's ability to modulate electronic, metabolic, and physicochemical characteristics. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated drug candidates, potentially enhancing their bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral amines and ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, or specialty surfactants with tailored properties.
• Chemical Biology Probes: Useful for incorporating fluorine tags into molecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	4-Fluoro-Cyclohexylamine
CAS No.	1314924-99-6
Molecular Formula	C6H12FN
Molecular Weight	117.17 g/mol
Synonyms	trans-4-Fluorocyclohexanamine; cis-4-Fluorocyclohexanamine; 4-Fluorocyclohexylamine; 4-Fluoro-1-cyclohexanamine; 4-Fluorocyclohexan-1-amine; (4-Fluorocyclohexyl)amine; 4-FCA; 4-Fluoro-cyclohexylamine (mixture of cis and trans isomers)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-Cyclohexylamine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 97.0% (typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.