Description

Benzenemethanamine, 3,4,5-Trifluoro-α,α-Dimethyl- is a high-value, multi-fluorinated aromatic amine building block. This compound is significant for its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and amine groups confer desirable properties.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Fluorinated Ligand Development: Employed in organometallic chemistry and catalysis to create novel ligands for transition metal complexes.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for fluorescent tags or molecular probes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical industry.

Basic Information

Product Name	Benzenemethanamine, 3,4,5-Trifluoro-α,α-Dimethyl-
CAS No.	1314740-53-8
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	3,4,5-Trifluoro-α,α-dimethylbenzylamine; (3,4,5-Trifluorophenyl)dimethylmethanamine; 1-(3,4,5-Trifluorophenyl)-N,N-dimethylmethanamine; α,α-Dimethyl-3,4,5-trifluorobenzylamine; 3,4,5-Trifluoro-α-methylbenzylamine, dimethyl-; Benzenemethanamine, α,α-dimethyl-3,4,5-trifluoro-
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 3,4,5-Trifluoro-α,α-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.