Description

Ethyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is a high-value, protected boronic ester derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the efficient and precise synthesis of novel target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or phenyl-substituted heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where conjugated aromatic systems are critical.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Ethyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate
CAS No.	1314397-95-9
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	3-((Ethoxycarbonyl)amino)phenylboronic acid pinacol ester; Ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate; 3-(Ethoxycarbonylamino)phenylboronic acid pinacol ester; 3-Aminophenylboronic acid pinacol ester, N-ethoxycarbonyl derivative; B-[3-[(Ethoxycarbonyl)amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Carbamic acid, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.