Description

3-Borono-2-Chlorobenzoic Acid is a high-value, multi-functional aromatic building block containing both boronic acid and carboxylic acid functional groups. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions, ligand synthesis, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides requiring specific chlorinated benzoic acid scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in transition metal catalysis and organoboron chemistry.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	3-Borono-2-Chlorobenzoic Acid
CAS No.	1314264-58-8
Molecular Formula	C7H6BClO4
Molecular Weight	200.38 g/mol
Synonyms	2-Chloro-3-boronobenzoic Acid; (2-Chloro-3-carboxyphenyl)boronic Acid; 3-Borono-2-chlorobenzoic Acid; Benzoic acid, 2-chloro-3-borono-; 2-Chloro-3-carboxybenzeneboronic Acid; B-(2-Chloro-3-carboxyphenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 3-Borono-2-Chlorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the stringent requirements of our global R&D and manufacturing clients. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (ICP-MS)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.