Description

1-(4-Iodo-3-Methoxy-Phenyl)-Ethanone is a high-purity, specialized aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated and methoxylated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing complex aryl-ether backbones.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the iodo-methoxyphenyl moiety can impart specific biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions, such as Suzuki or Sonogashira couplings.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, including charge-transport molecules or photoactive compounds for OLEDs and sensors.
• Chemical Biology Probe Development: Utilized to create tagged molecules or affinity probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1-(4-Iodo-3-Methoxy-Phenyl)-Ethanone
CAS No.	1314254-38-0
Molecular Formula	C9H9IO2
Molecular Weight	276.07 g/mol
Synonyms	4'-Iodo-3'-methoxyacetophenone; 1-(4-Iodo-3-methoxyphenyl)ethan-1-one; 3-Methoxy-4-iodoacetophenone; 4-Acetyl-2-iodoanisole; p-Iodo-m-anisyl methyl ketone; 1-Acetyl-4-iodo-3-methoxybenzene; 4-Iodo-3-methoxyacetophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Iodo-3-Methoxy-Phenyl)-Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.