Description

5,6-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4H-Pyrrolo[1,2-B]Pyrazole is a high-value, heterocyclic boronic ester derivative that serves as a critical synthetic intermediate. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to build novel molecular scaffolds for drug discovery, crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional organic electronic materials.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions to introduce the pyrrolopyrazole moiety into complex molecular architectures.
• Ligand & Catalyst Development: Utilized in the preparation of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Life Science Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	5,6-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4H-Pyrrolo[1,2-B]Pyrazole
CAS No.	1314138-13-0
Molecular Formula	C13H21BN2O2
Molecular Weight	248.13 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazole; 4H-Pyrrolo[1,2-b]pyrazole-3-boronic acid, 5,6-dihydro-, pinacol ester; 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid pinacol ester; 1314138-13-0; Pyrrolopyrazole boronic ester; Pinacol 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronate
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4H-Pyrrolo[1,2-B]Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and development documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.