Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. This compound matters because it provides a protected boronic acid functionality essential for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing the [1,2,4]triazolo[4,3-a]pyridine scaffold for oncology and CNS applications.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aryl/heteroaryl groups under mild conditions, widely used in medicinal chemistry and material science.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport materials and emissive layer components for display technologies.
• Ligand Synthesis for Catalysis: Intermediate for creating sophisticated bidentate or tridentate ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1314137-24-0
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine-6-boronic acid pinacol ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,4-triazolo[4,3-a]pyridine; 6-(Pinacolboranyl)-[1,2,4]triazolo[4,3-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-[1,2,4]triazolo[4,3-a]pyridine; 1314137-24-0; 6-Triazolopyridine boronic ester
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.