Description

3-Methyl-Benzo[D]Isoxazole-5-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, process development, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the benzisoxazole pharmacophore.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, via cross-coupling polymerization.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new C-C bond formation strategies and synthesizing novel chemical libraries.
• Ligand Synthesis: Can be utilized to prepare sophisticated ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Methyl-Benzo[D]Isoxazole-5-Boronic Acid Pinacol Ester
CAS No.	1314136-00-9
Molecular Formula	C₁₄H₁₈BNO₃
Molecular Weight	259.11 g/mol
Synonyms	3-Methylbenzo[d]isoxazol-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylbenzo[d]isoxazole; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]isoxazole; 3-Methyl-1,2-benzisoxazole-5-boronic acid pinacol ester; B-(3-Methylbenzo[d]isoxazol-5-yl)boronic acid pinacol ester; 1314136-00-9; 3-Methylbenzisoxazole-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Methyl-Benzo[D]Isoxazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.