Description

3-Fluorophenylboronic Acid Mida Ester is a specialized, protected boronic acid derivative designed for advanced synthetic applications. This compound is valued for its enhanced stability and controlled reactivity compared to its free boronic acid counterpart, making it a crucial building block in modern organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in cross-coupling reactions and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key protected synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biaryl or heterobiaryl motifs via Suzuki-Miyaura cross-coupling.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science: Serves as a precursor for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and molecular tags due to the selective reactivity of the Mida ester group.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new catalytic cycles in organometallic chemistry.
• Library Synthesis: Facilitates the parallel and combinatorial synthesis of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-Fluorophenylboronic Acid Mida Ester
CAS No.	1313614-50-4
Molecular Formula	C₁₃H₁₅BFNO₄
Molecular Weight	287.07 g/mol
Synonyms	N-Methyliminodiacetic Acid (MIDA) 3-Fluorophenylboronate; (3-Fluorophenyl)-MIDA-boronate; 3-Fluorophenylboronic Acid N-Methyliminodiacetic Acid Ester; MIDA Boronate of 3-Fluorophenylboronic Acid; [3-Fluorophenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)]-MIDA Ester; B-(3-Fluorophenyl)-N-methyliminodiacetic acid boronate
EINECS	Contact for details

Quality Control

Our 3-Fluorophenylboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.