Description

3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-9-Aza-Bicyclo[3.3.1]Non-2-Ene-9-Carboxylic Acid tert-Butyl Ester is a sophisticated, high-purity boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical key intermediate in the construction of complex nitrogen-containing heterocycles, prized for its stability and reactivity in cross-coupling reactions. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing bridged azabicyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable boronate ester reagent for the efficient formation of carbon-carbon bonds in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Potential precursor for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Serves as a valuable reagent for methodological development and the synthesis of complex natural product analogs.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-9-Aza-Bicyclo[3.3.1]Non-2-Ene-9-Carboxylic Acid tert-Butyl Ester
CAS No.	1313034-25-1
Molecular Formula	C19H32BNO4
Molecular Weight	349.28 g/mol
Synonyms	9-Aza-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[3.3.1]non-2-ene-9-carboxylic acid tert-butyl ester; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9-azabicyclo[3.3.1]non-2-ene-9-carboxylate; 9-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9-azabicyclo[3.3.1]non-2-ene; Bicyclo[3.3.1]nonane boronic ester derivative; Pinacol boronate ester of 9-Boc-9-azabicyclo[3.3.1]non-2-ene
EINECS	Contact for details

Quality Control

Our production of 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-9-Aza-Bicyclo[3.3.1]Non-2-Ene-9-Carboxylic Acid tert-Butyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.