Description

(2-[(2-Methoxyethyl)Amino]Pyrimidin-5-Yl)Boronic Acid CAS NO 1312942-15-6 is a specialized boronic acid derivative featuring a pyrimidine core, designed for advanced cross-coupling reactions in synthetic chemistry. This compound is a critical building block for medicinal chemistry and materials science, enabling the precise construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, essential in constructing biaryl and heteroaryl structures prevalent in drug candidates.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by incorporating the pyrimidine-boronic acid moiety into lead compounds.
• Material Science & OLED Development: Employed in the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or emissive layers in OLEDs.
• Chemical Biology & Probe Synthesis: Utilized for creating molecular probes and bioconjugates due to its reactive boronic acid group, which can be used for labeling or sensing applications.
• Library Synthesis for Drug Discovery: A valuable building block in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	(2-[(2-Methoxyethyl)Amino]Pyrimidin-5-Yl)Boronic Acid
CAS No.	1312942-15-6
Molecular Formula	C9H14BN3O3
Molecular Weight	223.04 g/mol
Synonyms	5-Pyrimidineboronic acid, 2-[(2-methoxyethyl)amino]-; 2-[(2-Methoxyethyl)amino]-5-pyrimidineboronic acid; (2-((2-Methoxyethyl)amino)pyrimidin-5-yl)boronic acid; 1312942-15-6; 2-(2-Methoxyethylamino)pyrimidine-5-boronic acid; 2-Methoxyethylamino-pyrimidin-5-yl-boronic acid; 5-Borono-2-[(2-methoxyethyl)amino]pyrimidine
EINECS	Contact for details

Quality Control

Our (2-[(2-Methoxyethyl)Amino]Pyrimidin-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Anhydrous basis)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.