Description

4-(Cyclohexylaminocarbonyl)Phenylboronic Acid Pinacol Ester is a high-value, advanced pharmaceutical intermediate and organic synthesis building block. This compound is specifically designed for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a stable, protected boronic ester partner for palladium-catalyzed carbon-carbon bond formation with aryl halides or triflates.
• Agrochemical Synthesis: Intermediate in the research and production of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and material science.
• OLED and Electronic Material Research: Building block for constructing complex organic molecules used in light-emitting diodes and other electronic applications.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized in the synthesis of bifunctional molecules for targeted protein degradation research.

Basic Information

Product Name	4-(Cyclohexylaminocarbonyl)Phenylboronic Acid Pinacol Ester
CAS No.	1312815-22-7
Molecular Formula	C19H28BNO3
Molecular Weight	329.24 g/mol
Synonyms	4-(Cyclohexylcarbamoyl)phenylboronic acid pinacol ester; [4-(Cyclohexylaminocarbonyl)phenyl]boronic acid pinacol ester; 4-(N-Cyclohexylcarbamoyl)benzeneboronic acid pinacol ester; 4-Carbamoylphenylboronic acid pinacol ester, N-cyclohexyl-; B-[4-[(Cyclohexylamino)carbonyl]phenyl]boronic acid pinacol ester; Cyclohexyl-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate (uncommon); 4-Cyclohexylaminocarbonylphenylboronic acid pinacol ester; 1312815-22-7
EINECS	Contact for details

Quality Control

Our 4-(Cyclohexylaminocarbonyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent hydrolysis of the boronic ester group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.