Description

4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a substituted piperidine moiety, making it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the creation of complex bioactive molecules.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of advanced polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity ligands for studying protein function and enzyme inhibition.
• Catalyst Ligand Synthesis: Used to create novel ligands for transition metal catalysts used in asymmetric synthesis and other specialized chemical transformations.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in academic and contract research organizations (CROs).

Basic Information

Product Name	4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenylboronic Acid
CAS No.	1312801-94-7
Molecular Formula	C14H22BNO3
Molecular Weight	263.14 g/mol
Synonyms	4-[2-(4-Methyl-1-piperidinyl)ethoxy]benzeneboronic acid; [4-[2-(4-Methylpiperidin-1-yl)ethoxy]phenyl]boronic acid; 4-(2-(4-Methylpiperidin-1-yl)ethoxy)phenylboronic acid pinacol ester (common protected form); 1-Methyl-4-[2-(4-boronatophenoxy)ethyl]piperidine; B-[4-[2-(4-Methyl-1-piperidinyl)ethoxy]phenyl]-boronic acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenylboronic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.