Description

3-Bromo-4-Methylphenylboronic Acid is a versatile organoboron compound that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecular architectures through efficient cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where the bromo and boronic acid functionalities allow for precise polymer and small-molecule construction.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects requiring high-purity boronic acid derivatives.

Basic Information

Product Name	3-Bromo-4-Methylphenylboronic Acid
CAS No.	1312765-69-7
Molecular Formula	C7H8BBrO2
Molecular Weight	214.86 g/mol
Synonyms	(3-Bromo-4-methylphenyl)boronic acid; 3-Bromo-p-tolylboronic acid; 4-Methyl-3-bromophenylboronic acid; B-(3-Bromo-4-methylphenyl)boronic acid; 3-Bromo-4-methylbenzeneboronic acid; Boronic acid, B-(3-bromo-4-methylphenyl)-; 1312765-69-7; 3-Br-4-MeC6H3B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.