Description

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole is a high-value organoboron building block, specifically a boronic ester derivative of a methoxythiazole heterocycle. This compound is critical for modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate the thiazole moiety.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules or inhibitors for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS No.	1312765-17-5
Molecular Formula	C10H16BNO3S
Molecular Weight	241.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxythiazole; 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Methoxythiazole-5-boronic acid pinacol ester; Thiazole-5-boronic acid, 2-methoxy-, pinacol ester; 1,3-Thiazole, 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Methoxy-5-(pinacolboryl)thiazole
EINECS	Contact for details

Quality Control

Every batch of our 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole is produced and tested under strict quality management protocols. We ensure high purity and lot-to-lot consistency through advanced analytical techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.