Description

tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Piperidine-1-Carboxylate is a high-value, protected piperidine boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, to construct complex molecular architectures. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing piperidine-containing drug candidates in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds to attach complex aryl or heteroaryl groups to the piperidine scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific piperidine motifs.
• Material Science: Serves as a precursor for functionalized polymers or organic electronic materials.
• Chemical Biology: Utilized in the synthesis of probes and ligands for studying biological targets and pathways.
• Library Synthesis: Ideal for creating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Piperidine-1-Carboxylate
CAS No.	1312713-37-3
Molecular Formula	C16H30BNO4
Molecular Weight	311.23 g/mol
Synonyms	1-Boc-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-piperidinecarboxylate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-piperidinecarboxylic acid tert-butyl ester; 1-N-Boc-3-Piperidineboronic Acid Pinacol Ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 3-Borono-1-N-Boc-piperidine Pinacol Ester; 1-Boc-3-Piperidinylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.