Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine (Ws204491) is a high-purity, advanced pharmaceutical intermediate and building block featuring a naphthylamine core with a pinacol boronate ester functional group. This compound is critically important for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to modern medicinal chemistry and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for the synthesis of complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aromatic rings, enabling the construction of complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer Chemistry: Monomer for creating functionalized polymers with specific electronic or optical properties.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation tools.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine (Ws204491)
CAS No.	1312611-42-9
Molecular Formula	C16H22BNO2
Molecular Weight	271.17 g/mol
Synonyms	2-Naphthylamine-6-boronic acid pinacol ester; 6-Aminonaphthalen-2-ylboronic acid pinacol ester; 2-Amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; Ws204491; 6-(Pinacolatoboryl)naphthalen-2-amine; 6-Amino-2-naphthaleneboronic acid pinacol ester; Naphthalen-2-amine, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to maximize shelf life and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.