Description

4-Pyrazolyl-Benzene Boronic Ester is a high-value boronic acid derivative and a versatile organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex biaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing heterocyclic biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aromatic coupling.
• Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology & Probe Synthesis: Employed in the creation of molecular probes and tags for studying biological systems.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	4-Pyrazolyl-Benzene Boronic Ester
CAS No.	1312478-63-9
Molecular Formula	C11H11BN2O2 (Typical for pinacol ester)
Molecular Weight	~214.03 g/mol (Contact for exact confirmed value)
Synonyms	4-(1H-Pyrazol-1-yl)benzeneboronic acid pinacol ester; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole; 4-Pyrazol-1-ylphenylboronic acid pinacol ester; (4-(1H-Pyrazol-1-yl)phenyl)boronic acid pinacol ester; 4-(1H-Pyrazol-1-yl)phenylboronic acid pinacol ester; Boronic acid, B-[4-(1H-pyrazol-1-yl)phenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Every batch of our 4-Pyrazolyl-Benzene Boronic Ester is manufactured and tested under strict quality management protocols. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including NMR, HPLC, and LC-MS. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.