Description

1-(p-Toluenesulfonyl)Pyrrole-2-Boronic Acid Mida Ester is a sophisticated, multi-functional organoboron building block designed for advanced synthetic chemistry. This compound is valued for its enhanced stability and controlled reactivity, making it a critical reagent for constructing complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable boronic acid equivalent for the formation of carbon-carbon bonds under mild conditions.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the development of targeted drug candidates, especially kinase inhibitors.
• Agrochemical Synthesis: Employed in the research and production of advanced crop protection agents and herbicides.
• Functional Materials Research: Facilitates the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for labeling and studying biological processes due to its selective reactivity.

Basic Information

Product Name	1-(p-Toluenesulfonyl)Pyrrole-2-Boronic Acid Mida Ester
CAS No.	1311484-50-0
Molecular Formula	C₁₄H₁₅BN₂O₄S
Molecular Weight	318.16 g/mol
Synonyms	1-(4-Methylbenzenesulfonyl)-1H-pyrrole-2-boronic acid, MIDA ester; 1-Tosylpyrrole-2-boronic acid MIDA ester; N-(4-Methylphenyl)sulfonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxamide; 1H-Pyrrole-1-carboxamide, N-[(4-methylphenyl)sulfonyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl]-, 2-(N-methyliminodiacetic acid) ester
EINECS	Contact for details

Quality Control

Our 1-(p-Toluenesulfonyl)Pyrrole-2-Boronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.