Description

1-(4-Bromo-2-Fluorophenyl)Butan-1-One is a high-purity organic building block characterized by its bromo- and fluoro-substituted aromatic ketone structure. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of specific halogenated motifs into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the halogenated phenyl group can contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of specialized monomers or ligands used in catalysis and advanced polymer systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), and exploring new synthetic pathways.
• Liquid Crystal & OLED Material Precursor: Potential use in the synthesis of fluorinated organic electronic materials due to its specific halogen pattern.

Basic Information

Product Name	1-(4-Bromo-2-Fluorophenyl)Butan-1-One
CAS No.	1311197-93-9
Molecular Formula	C₁₀H₁₀BrFO
Molecular Weight	245.09 g/mol
Synonyms	4'-Bromo-2'-fluorobutyrophenone; 1-(4-Bromo-2-fluorophenyl)-1-butanone; Butan-1-one, 1-(4-bromo-2-fluorophenyl)-; 4-Bromo-2-fluorobutyrophenone; 2-Fluoro-4-bromobutyrophenone; 1-Butanone, 1-(4-bromo-2-fluorophenyl)-; p-Bromo-o-fluorobutyrophenone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-2-Fluorophenyl)Butan-1-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.