Description

1-(4-Bromo-2-Fluorophenyl)Pentan-1-One is a high-purity fluorinated and brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both halogen substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the halogenated phenyl group can contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the synthesis of fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create more complex biaryl structures.
• Chemical Research: Employed in academic and industrial R&D labs as a standard building block for exploring new synthetic methodologies and constructing molecular libraries.
• Functional Material Precursor: Used in the development of specialty polymers, ligands for catalysis, and other advanced functional materials requiring halogenated aromatic components.

Basic Information

Item	Detail
Product Name	1-(4-Bromo-2-Fluorophenyl)Pentan-1-One
CAS No.	1311197-91-7
Molecular Formula	C11H12BrFO
Molecular Weight	259.12 g/mol
Synonyms	4'-Bromo-2'-fluorovalerophenone; 1-Pentanone, 1-(4-bromo-2-fluorophenyl)-; 4-Bromo-2-fluorovalerophenone; Valerophenone, 4'-bromo-2'-fluoro-; (4-Bromo-2-fluorophenyl) pentyl ketone; 1-(4-Brom-2-fluor-phenyl)-pentan-1-on; 4-Bromo-2-fluoro-1-pentanoylbenzene
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-2-Fluorophenyl)Pentan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We are committed to meeting the stringent requirements of research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.