Description

1,3,2-Dioxaborolane, 2-(4-Chloro-3-Ethoxyphenyl)-4,4,5,5-Tetramethyl- is a high-purity, organoboron building block of significant value in modern synthetic chemistry. This compound is specifically engineered to serve as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronate ester, widely used in pharmaceutical synthesis.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel drug candidates, particularly in constructing complex biaryl structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific chlorinated and ethoxylated phenyl motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Can be utilized as a precursor for bioconjugation reagents or in the development of enzyme inhibitors.
• Academic & Process Chemistry: A valuable tool for methodological development and scaling up synthetic routes in both academic and industrial R&D laboratories.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(4-Chloro-3-Ethoxyphenyl)-4,4,5,5-Tetramethyl-
CAS No.	1310956-28-5
Molecular Formula	C14H20BClO3
Molecular Weight	282.57 g/mol
Synonyms	2-(4-Chloro-3-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-Chloro-3-ethoxyphenyl)boronic acid pinacol ester; 4-Chloro-3-ethoxybenzeneboronic acid pinacol ester; 4-Chloro-3-ethoxyphenylboronic acid pinacol ester; 2-(4-Chloro-3-ethoxyphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 1,3,2-Dioxaborolane, 2-(4-chloro-3-ethoxyphenyl)-4,4,5,5-tetramethyl-; (4-Chloro-3-ethoxyphenyl)BPin; CAS 1310956-28-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity synthetic intermediates. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for prolonged periods; allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.