Description

Boronic Acid, B-[4-Chloro-3-(Difluoromethoxy)Phenyl]- is a high-purity, synthetically valuable organoboron building block, identified by CAS NO 1310949-72-4. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is engineered for researchers and process chemists in the life sciences sector who require reliable, high-quality intermediates to accelerate the development of novel active compounds. Its specific substitution pattern offers precise control in constructing complex biaryl architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the difluoromethoxy and chloro motifs for enhanced bioactivity and stability.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its ability to form stable carbon-carbon bonds.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities specializing in bespoke organic molecule production.

Basic Information

Product Name	Boronic Acid, B-[4-Chloro-3-(Difluoromethoxy)Phenyl]-
CAS No.	1310949-72-4
Molecular Formula	C7H6BClF2O3
Molecular Weight	218.38 g/mol
Synonyms	[4-Chloro-3-(difluoromethoxy)phenyl]boronic acid; (4-Chloro-3-(difluoromethoxy)phenyl)boronic acid; 4-Chloro-3-(difluoromethoxy)benzeneboronic acid; B-(4-Chloro-3-(difluoromethoxyphenyl)boronic Acid; 1310949-72-4; 4-Chloro-3-difluoromethoxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of Boronic Acid, B-[4-Chloro-3-(Difluoromethoxy)Phenyl]- is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent industry standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.