Description

4-(2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Morpholine is a high-value, synthetically versatile boronic ester derivative that serves as a critical building block in modern organic synthesis. Its primary value lies in enabling the efficient construction of complex molecular architectures through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides, leveraging the morpholine moiety for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where the boronate group facilitates precise molecular assembly.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of chemical probes for target identification and validation.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects requiring specific, high-purity boronic ester intermediates.

Basic Information

Item	Details
Product Name	4-(2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Morpholine
CAS No.	1310707-19-7
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	4-(2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine; 2-Methyl-4-morpholinophenylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylphenylmorpholine; 2-Methyl-4-(morpholin-4-yl)phenylboronic acid pinacol ester; (4-Morpholino-3-methylphenyl)boronic acid pinacol ester; 1310707-19-7; 4-(2-Methyl-4-(pinacolatoboron)phenyl)morpholine
EINECS	Contact for details

Quality Control

Our production of 4-(2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Morpholine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.