Description

3-Bromo-5-Fluorophenoxy(tert-Butyl)Dimethylsilane is a high-value organosilicon intermediate featuring a protected phenol group. This compound is critical for synthetic chemists as it enables the selective functionalization of aromatic systems in complex multi-step syntheses. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted phenol or fluorophenol motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo-fluoro-phenoxy moiety is required.
• Material Science Research: Serves as a precursor for creating functionalized silanes used in surface modification, adhesion promoters, and specialty polymers.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and organometallic chemistry.

Basic Information

Item	Details
Product Name	3-Bromo-5-Fluorophenoxy(tert-Butyl)Dimethylsilane
CAS No.	1310697-89-2
Molecular Formula	C₁₂H₁₈BrFO₃Si
Molecular Weight	329.26 g/mol
Synonyms	tert-Butyl(3-bromo-5-fluorophenoxy)dimethylsilane; (3-Bromo-5-fluorophenoxy)(tert-butyl)dimethylsilane; 3-Bromo-5-fluoro-1-[(tert-butyl)dimethylsilyl]oxybenzene; 1-[(tert-Butyldimethylsilyl)oxy]-3-bromo-5-fluorobenzene; TBDMS 3-Bromo-5-fluorophenyl ether; 3-Bromo-5-fluorophenyl tert-butyldimethylsilyl ether; 3-Br-5-F-PhO-TBDMS
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluorophenoxy(tert-Butyl)Dimethylsilane is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.