Description

(3Z,3'Z)-4,4'-(1,3-Phenylene)Bis(1,1,1-Trifluoro-4-Hydroxybut-3-En-2-One) CAS NO 1310684-78-6 is a high-purity, specialized fluorinated diketone building block. This compound is valued for its unique molecular architecture, featuring a central phenylene linker flanked by two trifluoromethylated β-diketone arms, which provides exceptional utility in advanced organic synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules, particularly as a precursor for heterocyclic compounds and metal-chelating ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated or metal-chelating motifs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, where the fluorine atoms and diketone functionality can enhance biological activity and environmental stability.
• Coordination Chemistry & Catalysis: Serves as a versatile ligand precursor for transition metals, enabling the creation of catalysts for asymmetric synthesis and polymerization reactions.
• Advanced Material Development: Employed in the research of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized to develop fluorescent sensors or affinity tags that exploit its metal-binding properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including cyclization and cross-coupling reactions.

Basic Information

Product Name	(3Z,3'Z)-4,4'-(1,3-Phenylene)Bis(1,1,1-Trifluoro-4-Hydroxybut-3-En-2-One)
CAS No.	1310684-78-6
Molecular Formula	C16H8F6O4
Molecular Weight	378.22 g/mol
Synonyms	1,3-Phenylenebis(1,1,1-trifluoro-4-hydroxybut-3-en-2-one); 4,4'-(1,3-Phenylene)bis(1,1,1-trifluoro-4-hydroxy-3-buten-2-one); (Z,Z)-1,3-Phenylenebis(4,4,4-trifluoro-3-hydroxybut-2-en-1-one); 1,3-Bis(4,4,4-trifluoro-3-hydroxy-1-oxobut-2-en-1-yl)benzene; TFHBE; Bis(trifluoromethyl) diketone phenylene derivative
EINECS	Contact for details

Quality Control

Our (3Z,3'Z)-4,4'-(1,3-Phenylene)Bis(1,1,1-Trifluoro-4-Hydroxybut-3-En-2-One) is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), isomeric purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
(Z,Z)-Isomeric Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.