Description

6-(4-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazolylpyridine scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Employed in the modular construction of bifunctional molecules for targeted protein degradation research.
• Ligand Synthesis: Useful for preparing sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	6-(4-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310405-03-8
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	6-(4-Methyl-1H-pyrazol-1-yl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(4-methyl-1H-pyrazol-1-yl)pyridine; 6-(4-Methylpyrazol-1-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol 6-(4-Methyl-1H-pyrazol-1-yl)pyridine-2-boronate; 1310405-03-8; Boronic acid, B-[6-(4-methyl-1H-pyrazol-1-yl)-2-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 6-(4-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is produced and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including NMR, HPLC, and LC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.