Description

4-Bromo-5-Methyl-Thiophene-2-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a thiophene-substituted boronic ester. This compound matters for its crucial role as a key intermediate in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those containing thiophene heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can impart specific biological activity.
• Material Science & OLED Development: Serves as a building block for creating novel organic semiconductors, conductive polymers, and light-emitting materials for electronic devices.
• Ligand & Catalyst Design: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new synthetic methodologies and constructing diverse chemical libraries.
• Fine Chemical Production: Used in the multi-step synthesis of other high-purity, specialty fine chemicals and complex organic molecules.

Basic Information

Item	Detail
Product Name	4-Bromo-5-Methyl-Thiophene-2-Boronic Acid Pinacol Ester
CAS No.	1310404-98-8
Molecular Formula	C11H16BBrO2S
Molecular Weight	303.02 g/mol
Synonyms	4-Bromo-5-methylthiophene-2-boronic acid pinacol ester; 2-(4-Bromo-5-methylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methyl-4-bromothiophene-2-boronic acid pinacol ester; (4-Bromo-5-methyl-2-thienyl)boronic acid pinacol ester; 4-Bromo-5-methyl-2-thiopheneboronic acid pinacol ester; Pinacol (4-bromo-5-methylthiophen-2-yl)boronate
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Methyl-Thiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.