Description

2-Methylthiazol-4-Ylboronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in enabling the efficient and selective construction of complex heterocyclic molecules, which are core scaffolds in numerous active compounds. This reagent is critically needed by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing drug candidates containing the 2-methylthiazole moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Catalyst Ligand Precursor: Can be utilized in the development of novel ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs producing specialized, high-value compounds for clients.

Basic Information

Product Name	2-Methylthiazol-4-Ylboronic Acid Pinacol Ester
CAS No.	1310404-96-6
Molecular Formula	C10H16BNO2S
Molecular Weight	225.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylthiazole; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Methylthiazole-4-boronic acid pinacol ester; 2-Methyl-4-thiazoleboronic acid pinacol ester; (2-Methylthiazol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Methylthiazol-4-Ylboronic Acid Pinacol Ester is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with the standards required for cGMP intermediate production and high-throughput research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.