Description

6-(Cyclobutoxy)Pyridine-2-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a versatile building block for the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the creation of complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing pyridine and cyclobutyl ether motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Serves as a monomer or precursor for creating novel organic electronic materials, ligands, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: A dedicated reagent for palladium-catalyzed coupling reactions to form biaryl and other conjugated systems efficiently.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, inhibitors, and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	6-(Cyclobutoxy)Pyridine-2-Boronic Acid
CAS No.	1310404-90-0
Molecular Formula	C9H12BNO3
Molecular Weight	193.01 g/mol
Synonyms	2-Borono-6-(cyclobutoxy)pyridine; 6-Cyclobutoxypyridine-2-boronic acid; (6-(Cyclobutoxy)pyridin-2-yl)boronic acid; Pyridine, 6-(cyclobutoxy)-2-borono-; 1310404-90-0; 6-Cyclobutoxy-2-pyridineboronic acid; 2-Pyridineboronic acid, 6-(cyclobutoxy)-
EINECS	Contact for details

Quality Control

Our 6-(Cyclobutoxy)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as boronic acid)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.