Description

5-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, advanced pharmaceutical intermediate and organic synthesis building block. This compound matters for its crucial role as a key precursor in modern cross-coupling reactions, particularly the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aromatic amine-boronate structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic semiconductors and emissive layer materials in display technology.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester group makes it an ideal, stable reagent for palladium-catalyzed carbon-carbon bond formation under mild conditions.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating libraries of compounds for screening.

Basic Information

Product Name	5-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1310404-85-3
Molecular Formula	C₁₃H₂₀BNO₃
Molecular Weight	249.12 g/mol
Synonyms	2-Amino-4-methoxyphenylboronic acid pinacol ester; 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; (2-Amino-4-methoxyphenyl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methoxyaniline; 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; Aniline, 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize degradation due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.