Description

5-Formyl-6-Methoxypyridine-3-Boronic Acid Pinacol Ester is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a formyl group and a protected boronic acid moiety, makes it an indispensable reagent for constructing complex heterocyclic systems via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients. Its reliable performance and consistent quality are essential for accelerating drug discovery and material science projects.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in biochemical assays and diagnostic tool development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) batches.

Basic Information

Product Name	5-Formyl-6-Methoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	1310404-57-9
Molecular Formula	C13H18BNO4
Molecular Weight	263.10 g/mol
Synonyms	(5-Formyl-6-methoxypyridin-3-yl)boronic acid pinacol ester; 6-Methoxy-5-pyridinecarboxaldehyde-3-boronic acid pinacol ester; 3-Formyl-2-methoxypyridine-5-boronic acid pinacol ester; 5-Formyl-6-methoxy-3-pyridineboronic acid pinacol ester; Pinacol (5-formyl-6-methoxy-3-pyridyl)boronate; 1310404-57-9; Boronic acid, B-(5-formyl-6-methoxy-3-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of 5-Formyl-6-Methoxypyridine-3-Boronic Acid Pinacol Ester is manufactured and tested under strict quality management protocols to ensure it meets the exacting standards required for research and commercial synthesis. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.