Description

3-Formylpyridine-4-Boronic Acid Pinacol Ester is a high-value, multifunctional heterocyclic building block essential for modern synthetic chemistry. This compound is specifically engineered to serve as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in next-generation herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized bidentate ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as novel polymers and small molecules for OLEDs and OFETs.
• Chemical Biology Probes: Utilized to build bioconjugatable probes and tags for target identification and protein labeling studies.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs serving the global life sciences industry.

Basic Information

Product Name	3-Formylpyridine-4-Boronic Acid Pinacol Ester
CAS No.	1310404-20-6
Molecular Formula	C₁₃H₁₈BNO₃
Molecular Weight	247.10 g/mol
Synonyms	4-Formylpyridine-3-boronic acid pinacol ester; (4-Formyl-3-pyridinyl)boronic acid pinacol ester; 3-Pyridinecarboxaldehyde, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbaldehyde; 3-Formyl-4-pyridinylboronic acid pinacol ester; 4-Borono-3-formylpyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Formylpyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor purity grades to meet specific project requirements from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.