Description

6-(tert-Butoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic ester derivative, a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient, selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, process development, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl halides and boronic acids/esters, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for the synthesis of tagged molecules and probes for studying biological systems and target engagement.

Basic Information

Product Name	6-(tert-Butoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310404-19-3
Molecular Formula	C₁₇H₂₆BNO₄
Molecular Weight	319.21 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-[(2-methylpropan-2-yl)oxycarbonyl]pyridine; 6-(Boc)-2-Pyridineboronic Acid Pinacol Ester; 2-(N-Boc-amino)-6-pyridineboronic Acid Pinacol Ester; tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate; 6-Boc-Pyridine-2-Boronic Acid Pinacol Ester; 2-Pyridineboronic acid, 6-[[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester, pinacol boronate
EINECS	Contact for details

Quality Control

Every batch of 6-(tert-Butoxycarbonyl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with high-purity standards suitable for research and commercial applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.