Description

6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyrazole-pyridine motifs.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aryl or heteroaryl groups.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of molecular probes for biological target identification.

Basic Information

Product Name	6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310404-12-6
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	6-(3-Methyl-1H-pyrazol-1-yl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(3-methyl-1H-pyrazol-1-yl)pyridine; 6-(3-Methylpyrazol-1-yl)pyridine-2-boronic acid pinacol ester; 6-(3-Methyl-1H-pyrazol-1-yl)-2-pyridineboronic acid pinacol ester; Boronic acid, B-[6-(3-methyl-1H-pyrazol-1-yl)-2-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.