Description

tert-Butyl 4-(2-[4-(4,4,5,5-Tetramethyl[1,3,2]Dioxaborolan-2-Yl)Phenoxy]Ethyl)Piperazine-1-Carboxyla is a high-purity, advanced pharmaceutical intermediate featuring a key boronic ester functional group. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex carbon-carbon bonds. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral drug discovery pipelines.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl and other C-C bonds under mild conditions, crucial for constructing complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized in the design and synthesis of bifunctional molecules for targeted protein degradation.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in university and CRO laboratory settings.

Basic Information

Product Name	tert-Butyl 4-(2-[4-(4,4,5,5-Tetramethyl[1,3,2]Dioxaborolan-2-Yl)Phenoxy]Ethyl)Piperazine-1-Carboxyla
CAS No.	1310404-00-2
Molecular Formula	C23H37BN2O5
Molecular Weight	432.36 g/mol
Synonyms	1-Boc-4-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethyl]piperazine; tert-Butyl 4-[2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethyl]piperazine-1-carboxylate; 4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperazine-1-carboxylic acid tert-butyl ester; BOC-Piperazine Boronic Ester; 1,3,2-Dioxaborolane, 2-[4-[2-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]ethoxy]phenyl]-4,4,5,5-tetramethyl-
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-[4-(4,4,5,5-Tetramethyl[1,3,2]Dioxaborolan-2-Yl)Phenoxy]Ethyl)Piperazine-1-Carboxyla is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and structural integrity, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.