Description

6-Dimethylaminopyridine-2-Boronic Acid Pinacol Ester is a versatile and highly valuable organoboron building block. Its core value lies in its dual functionality, combining a reactive boronic ester group with a dimethylaminopyridine moiety, making it a critical intermediate for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise, high-yield synthesis of complex molecules, particularly for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for coupling reactions to form biaryl structures common in drug molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, where precise molecular architecture is crucial.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Research: A fundamental reagent in academic and industrial R&D for exploring new carbon-carbon bond-forming methodologies and constructing complex molecular libraries.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and pigments that incorporate substituted pyridine and biphenyl units.

Basic Information

Product Name	6-Dimethylaminopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310385-02-4
Molecular Formula	C13H21BN2O2
Molecular Weight	248.13 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(dimethylamino)pyridine; 6-(Dimethylamino)pyridine-2-boronic acid pinacol ester; 2-(Dimethylamino)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; DMAP-BPin; 6-DMAP-2-BPin; 2-Borono-6-(dimethylamino)pyridine pinacol ester; N,N-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Dimethylaminopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available for all commercial quantities. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to maintain optimal stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.