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3-Methoxythiophene-2-Boronic Acid Pinacol Ester CAS NO 1310384-98-5


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CAS No.:1310384-98-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Methoxythiophene-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Critical for synthesizing novel drug candidates, particularly those containing functionalized thiophene scaffolds for therapeutic applications.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored biological activity.
  • Material Science Research: Serves as a precursor for creating conjugated polymers and organic electronic materials for OLEDs, OFETs, and sensors.
  • Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways.
  • Catalyst & Ligand Development: Acts as a building block for novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
  • Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name 3-Methoxythiophene-2-Boronic Acid Pinacol Ester
CAS No. 1310384-98-5
Molecular Formula C11H17BO3S
Molecular Weight 240.13 g/mol
Synonyms 2-(3-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methoxy-2-thienylboronic acid pinacol ester; 2-(3-Methoxythien-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methoxythiophene-2-boronic acid neopentyl glycol ester (common alternative); Pinacol (3-Methoxy-2-thienyl)boronate; (3-Methoxythiophen-2-yl)boronic acid pinacol ester; Boronic acid, B-(3-methoxy-2-thienyl)-, 1,1-dimethylethyl ester (related); Thiophene-2-boronic acid, 3-methoxy-, pinacol ester
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Quality Control

Our 3-Methoxythiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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