Description

4-Carbamoylpyridine-3-Boronic Acid Pinacol Ester is a high-value boronic ester derivative, a crucial protected intermediate in modern synthetic chemistry. Its core value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing functionalized pyridine cores.
• Suzuki-Miyaura Cross-Coupling Reagent: Used for the selective formation of carbon-carbon bonds to introduce the 3-substituted pyridine moiety into larger molecular architectures.
• Agrochemical Synthesis: Employed in the research and development of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Material Science Research: Used in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological systems.

Basic Information

Product Name	4-Carbamoylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1310384-92-9
Molecular Formula	C13H19BN2O3
Molecular Weight	262.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinamide; 4-Carbamoyl-3-pyridinylboronic acid pinacol ester; Isonicotinamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Boronoisonicotinamide pinacol ester; 4-Cyano-3-pyridinylboronic acid pinacol ester (hydrolyzed/related form); PINACOL 3-CARBAMOYLPYRIDIN-4-YLBORONATE
EINECS	Contact for details

Quality Control

Every batch of 4-Carbamoylpyridine-3-Boronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.