Description

6-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester is a high-purity, functionalized pyridine boronic ester derivative, a critical building block in modern synthetic chemistry. This compound matters because it serves as a versatile intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require complex, functionalized heterocyclic cores.
• Material Science & OLED Development: Serves as a precursor for creating electron-transport materials, ligands for metal-organic frameworks (MOFs), and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).
• Ligand Synthesis for Catalysis: Intermediate for preparing sophisticated bidentate or tridentate ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	6-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310384-91-8
Molecular Formula	C₁₂H₁₇BN₂O₄
Molecular Weight	264.09 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-3-nitropyridine; 6-Methyl-3-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Nitro-6-methylpyridine-2-boronic acid pinacol ester; (6-Methyl-3-nitropyridin-2-yl)boronic acid pinacol ester; 1310384-91-8; 2-Borono-6-methyl-3-nitropyridine pinacol ester; 6-Methyl-3-nitropyridine-2-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality assurance ensures reliable performance in your sensitive cross-coupling applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) in a desiccator to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.