Description

Boc-5-Amino-3-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound is a critical building block in the synthesis of complex molecules, particularly for the pharmaceutical industry, where it enables efficient cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• API Synthesis: Used in the research and process development of novel Active Pharmaceutical Ingredients (APIs), especially in oncology and CNS therapeutic areas.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for creating complex organic molecules and libraries for screening.
• Agrochemical Development: Employed in the synthesis of advanced crop protection agents and herbicides that require specific heterocyclic architectures.
• Material Science: Potential use in the synthesis of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).

Basic Information

Product Name	Boc-5-Amino-3-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310384-90-7
Molecular Formula	C17H27BN2O4
Molecular Weight	334.22 g/mol
Synonyms	tert-Butyl (3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-Amino-3-methylpyridine-2-boronic acid pinacol ester, N-Boc protected; Boc-5-Amino-3-Methyl-2-pyridineboronic Acid Pinacol Ester; N-Boc-5-Amino-3-methylpyridine-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Boc-5-Amino-3-Methylpyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.