Description

4-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester is a high-purity, functionalized pyridine boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with targeted activity.
• Material Science: Employed in the development of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: A pivotal reagent for forming carbon-carbon bonds between aryl/heteroaryl groups under mild conditions.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biological target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	4-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310384-89-4
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-3-nitropyridine; 4-Methyl-3-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Nitro-4-methylpyridine-2-boronic acid pinacol ester; Pinacol (4-Methyl-3-nitro-2-pyridinyl)boronate; (4-Methyl-3-nitropyridin-2-yl)boronic acid pinacol ester; Boronic acid, B-(4-methyl-3-nitro-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI); 1310384-89-4; 4-Methyl-3-nitropyridine-2-boronic acid neopentyl glycol ester (common alternative)
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-Nitropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures material consistency and reliability for your most demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.