Description

Methyl Pyridine-2-Boronic Acid Pinacol Ester-5-Carboxylate is a high-value, multifunctional organoboron building block designed for advanced synthetic chemistry. This compound is essential for facilitating efficient cross-coupling reactions, particularly in the construction of complex heterocyclic systems. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with complex pyridine-based structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for palladium-catalyzed carbon-carbon bond formation to create biaryl and heteroaryl structures.
• Material Science Research: Precursor for the development of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Medicinal Chemistry: Enables the synthesis of molecular probes and compound libraries for drug discovery and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring specialized boronic acid derivatives.

Basic Information

Item	Details
Product Name	Methyl Pyridine-2-Boronic Acid Pinacol Ester-5-Carboxylate
CAS No.	1310384-84-9
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	5-(Methoxycarbonyl)pyridine-2-boronic acid pinacol ester; Methyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate; 2-Pyridineboronic acid, 5-(methoxycarbonyl)-, 1,1-dimethylethyl ester; Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinic acid methyl ester; Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl Pyridine-2-Boronic Acid Pinacol Ester-5-Carboxylate is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.