Description

(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophen-3-Yl)Methanol is a high-value, functionalized organoboron building block, specifically a boronic ester derivative of thiophene methanol. This compound is essential for modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex heterocyclic molecules and advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly those containing thiophene or fused heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific thiophene-based architectures.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized to create tagged molecules or bioconjugates for studying biological processes and target engagement.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into polymeric materials.

Basic Information

Product Name	(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophen-3-Yl)Methanol
CAS No.	1310384-43-0
Molecular Formula	C11H17BO3S
Molecular Weight	240.13 g/mol
Synonyms	3-(Hydroxymethyl)thiophene-2-boronic acid pinacol ester; (3-(Hydroxymethyl)thiophen-2-yl)boronic acid pinacol ester; 2-(3-(Hydroxymethyl)thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Thiophene-3-methanol, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol (3-(hydroxymethyl)thiophen-2-yl)boronate
EINECS	Contact for details

Quality Control

Our (2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophen-3-Yl)Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. All batches are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.